Can You Reverse the Effects of the Abortion Pill?

July 6, 2025

If you’ve taken the first abortion drug, mifepristone, and are now feeling unsure, you may be wondering if it’s too late to continue the pregnancy. The good news is that it may still be possible to reverse the effects of mifepristone. This process is known as Abortion Pill Reversal (APR), and it has helped many women who experienced regret.

Heart to Heart provides no-cost, confidential APR referrals to help you get the care and answers you need. Keep reading to learn more about how this protocol works.

How Does the Abortion Pill Work?

First, it’s crucial to learn how the abortion pill ends a pregnancy. This process involves two drugs. The first drug, mifepristone, blocks progesterone, a natural hormone your body produces to sustain the pregnancy. Without progesterone, the uterine lining thins and the pregnancy ends.

The second drug, misoprostol, is taken afterward. It causes the uterus to contract and expel the pregnancy through the vagina. Once misoprostol has been taken, the process cannot be reversed.

What Is Abortion Pill Reversal (APR)?

APR works by providing extra progesterone to counteract the effects of mifepristone. This hormone has been safely used for decades to support women during early pregnancy and reduce the risk of miscarriage. 

APR has been successful in many cases when started as soon as possible—ideally within 24 to 48 hours. One study reported success rates between 64 and 68%. Although not guaranteed, APR offers a real chance to continue your pregnancy.

Is It Safe?

Progesterone has a long track record and is not known to increase the risk of birth defects beyond what’s observed in the general population. 

If you’ve taken mifepristone but are now feeling uncertain, it is critical to act quickly and speak with a medical professional who prescribes APR.

What Should You Do Next?

At Heart to Heart, we’re here to support you with compassion, understanding, and resources you can trust. We can refer you for APR and walk with you through every step of this unexpected journey. 

You can also contact the 24/7 Abortion Pill Reversal Helpline. They can connect you to a provider near you who offers APR and will guide you through the next steps. The process is time-sensitive, so reaching out as soon as possible gives you the best chance of success.

You’re Not Alone

Experiencing regret after taking the first abortion pill can be emotional and overwhelming, but you’re not alone. Help is available, and there is still hope. 

Contact our nurses at (307) 745-3444 to learn more. We’re here for you.

Heart to Heart does not provide or refer for abortions.

All abortion information sourced in this blog is based on accurate information at the time of writing.